To be honest, I don t think there is something that s comparable to Node.js at the moment.
Why? Well basically because of the fact that JavaScript was single threaded from the start off, this made the language evolve in what it is today, a language that s perfectly fit for asynchronous programming, like you do it in Node.js.
Functions being first class objects, as well as having closures is a must if you want a Node like experience. For example you could just as well wrap plain C around the event lib and use that. But how much fun would that be? Even with twisted, you don t get even near the Node.js experience.
Second point is that Node.js has - except for the sync functions of the fs
modules - no blocking functions, so while you can certainly do this style of programming in Python, you never know for sure if that library call isn t going to block your whole program. And kill the throughput of your server.
Also Node is fast, like in REALLY fast. V8 is definitely way ahead of Python and Ruby, yes you can write C-Extensions for both, but you can just as well do that for Node.js. Another plus point of using V8, Google is investing a ton of time/money into that Engine, another up to 2x improvement is already on the way with Crankshaft.
Node.js has more plus points, it s a complete framework (while Twisted is mainly async networking) and it s JavaScript.
The latter one may sound stupid, but the ability to re-use code and not having to do context switching , as well as being able to use mature frameworks for DOM manipulation (well, that is as soon as jsom gets into a more stable state) is another killer feature.
If you haven t done yet, I recommend you watch a couple of the talks listed on our Tag Wiki.
Especially the YUI one shows what possibilities await us in the near future.
So to sum it all up:
Although there are quite some frameworks out there that have an event loop, just having the loop itself won t give you the same experience as Node.js, so you should not expect a comparable experience when doing stuff in C or Java for example.